Award
NIH Reporter #1R21AI190597-01A1
Mast Cell G-protein Coupled Receptors in Immune Modulation of colitis
Recipient
University of Pennsylvania
Award Amount
$446,875.00
Ceiling
$446,875.00
Awarded
August 11, 2025
Identifier
1R21AI190597-01A1
NIH grant awarded to University of Pennsylvania to study the role of mast cell G-protein coupled receptors in immune modulation of ulcerative colitis using mouse models.
Description
This project aims to investigate how SNPs in MRGPRX2 affect disease phenotype and the role of this receptor in ulcerative colitis pathogenesis using genetically modified mouse models.