Award
NIH Reporter #1RF1AG091410-01A1
Clarifying the interplay between herpesvirus infection and reactivation, immune responses, APOE genotype, and development of tau-pathology
Recipient
Harvard University D/B/A Harvard School of Public Health, Boston, MA, United States
Award Amount
$3,280,861.00
Ceiling
$3,280,861.00
Awarded
September 08, 2025
Identifier
1RF1AG091410-01A1
NIH-funded research project investigating the relationship between herpesvirus infections, immune responses, APOE genotype, and Alzheimer's disease pathology using longitudinal cohort data and advanced biomarker analysis.
Description
This research project funded by the National Institute on Aging (NIA) at NIH focuses on studying the role of microbial infections, particularly herpesviruses, in triggering Alzheimer's disease (AD). It involves analyzing archived samples from the Nurses’ Health Study cohort to assess immune responses and development of tau-pathology in relation to APOE genotype and other AD risk factors.