Award
NIH Reporter #5R35GM147406-05
Elucidating and Directing Heteromolecular Mechanobiology with Nanoengineered Cell Interfaces
Recipient
New York University School of Medicine
Award Amount
$388,159.00
Ceiling
$388,159.00
Awarded
August 28, 2026
Identifier
5R35GM147406-05
The award supports research to develop nanoengineered cell interfaces to study and manipulate cellular mechanobiology, addressing key molecular and cellular mechanisms for improved diagnostics and therapies.
Description
This project aims to create artificial cell interfaces with multiplexed physicochemical features to elucidate and direct cellular functions, focusing on heteromolecular mechanobiology for cell-extracellular matrix and cell-cell signaling using fibroblast and T cell models. The research combines top-down nanotechnology and bottom-up synthetic biology to develop advanced diagnostic and therapeutic methods.