Award
The University of Texas Health Science Center at Houston 1R35GM166414-01
Dynamic Regulation of Proton-activated Chloride Channel in Physiology and Pathology
Recipient
University of Texas Health Science Center Houston
Award Amount
$429,000.00
Ceiling
$429,000.00
Awarded
July 22, 2026
Identifier
1R35GM166414-01
Research project awarded to study the proton-activated chloride channel to develop treatments for acidosis-related brain injury.
Description
This project aims to study the conformational dynamics and regulation of the proton-activated chloride channel (PAC) to develop new treatments for acidosis-related brain injury. The research involves functional, biophysical, and lipidomic approaches across multiple areas of investigation.