Award
National Institute of Allergy and Infectious Diseases 5R37AI051334-22
Extracellular Matrix Adhesins of Treponema pallidum
Recipient
University of Victoria
Award Amount
$316,014.00
Ceiling
$316,014.00
Awarded
December 03, 2025
Identifier
5R37AI051334-22
Research project funded by NIAID to study the pathogenic mechanisms of Treponema pallidum to develop prevention strategies for syphilis.
Description
This project aims to increase understanding of the pathogenic mechanisms used by Treponema pallidum to disseminate via the bloodstream and cause disease. The research focuses on host cell signaling pathways, identification of bacterial proteins involved in immune evasion, and in vivo assessment of these proteins' roles in disease pathogenesis. The goal is to develop strategies to prevent syphilis infection.