Award
NIH Reporter #11170835
How do microbiota determine neuronal function and protect against neurodegeneration?
Recipient
University of Massachusetts Medical School, Worcester
Award Amount
$647,979.00
Ceiling
$647,979.00
Awarded
September 17, 2024
Identifier
11170835
NIH-funded research project by the National Institute on Aging to study how microbiota affect neuronal function and protect against neurodegeneration using C. elegans as a model. The project aims to identify protective microbiota and mechanisms, with a focus on vitamin B12 and bacterial roles in neuroprotection.
Description
The project focuses on understanding how microbiota influence neuronal function and neurodegeneration, leveraging the model organism C. elegans. It aims to identify microbiota, metabolites, and mechanisms that protect neuronal integrity. The project involves microbiome research, neurobiology, and molecular mechanisms, emphasizing the role of vitamin B12 and other bacteria in neuroprotection. It is funded by the NIH, specifically the National Institute on Aging, and involves collaboration with the University of Massachusetts Medical School, Worcester.