Award
NIH Reporter #1F31HG014981-01
Increasing the throughput of variant classification with multiplexed prime editing and single cell long-read technologies
Recipient
Northwestern University, Chicago, IL
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
April 28, 2026
Identifier
1F31HG014981-01
The award supports research to enhance variant classification using advanced gene editing and single-cell transcriptomic technologies to improve diagnosis and treatment of genetic disorders.
Description
This project aims to develop innovative tools, including multiplexed gene editing strategies and single-cell long-read transcriptomic assays, to improve the classification of variants of uncertain significance (VUS) across a wide range of genes, contributing to better diagnostics and health outcomes for individuals with genetic disorders.