Award
National Institute on Alcohol Abuse and Alcoholism 5U01AA014095-24
INIA Stress and Chronic Alcohol Interactions: Role of Dynorphin/KOR and Oxytocin Systems in Stress-Enhanced Alcohol Drinking, Relapse, and Impaired Behavioral Flexibility
Recipient
MEDICAL UNIVERSITY OF SOUTH CAROLINA
Awarded
February 20, 2026
Identifier
5U01AA014095-24
Research project awarded by NIAAA to study the role of Dynorphin/KOR and Oxytocin systems in stress-enhanced alcohol drinking and relapse, aiming to develop better interventions for alcohol use disorder.
Description
The project focuses on neurocircuitry involved in stress and alcohol interactions, employing transgenic mice, pharmacological, chemogenetic, and CRISPR/Cas9 approaches. The ultimate goal is to develop more effective interventions for stress-related alcohol use disorder and relapse.