Award
National Heart, Lung, and Blood Institute 5R01HL164795-04
Troponin I phosphorylation as a novel novel cardiac inotrope
Recipient
Ohio State University, Columbus, OH, United States
Award Amount
$618,446.00
Ceiling
$618,446.00
Awarded
March 10, 2026
Identifier
5R01HL164795-04
The project investigates site-specific phosphorylation of Troponin I to enhance cardiac function safely, aiming to develop a novel therapeutic approach for heart disease.
Description
This project aims to establish the effects and mechanisms of site-specific phosphorylation of Troponin I (TnI) to improve cardiac function in normal and diseased hearts. The study will evaluate the safety and efficacy of this phosphorylation on human cardiac tissue, with the goal of developing a novel therapeutic approach for heart disease.