Award
NIH Reporter #5UH3DA047720-05
Evaluation of safety and pharmacokinetics of naltrexone implant
Recipient
New York State Psychiatric Institute DBA Research Foundation for Mental Hygiene, Inc.
Award Amount
$3,864,542.00
Ceiling
$3,864,542.00
Awarded
February 27, 2023
Identifier
5UH3DA047720-05
The award supports the development and evaluation of a long-acting naltrexone implant to treat opioid use disorder, focusing on safety, pharmacokinetics, and bioequivalence to improve long-term relapse prevention.
Description
This project aims to develop and evaluate a long-acting subcutaneous implant formulation of naltrexone for the treatment of opioid use disorder (OUD). The study will assess safety, pharmacokinetics, and bioequivalence compared to existing treatments, with the goal of providing a safe, effective, and long-term relapse prevention method.