Award
NIH Reporter #11322757
Investigating the combined role of APOE4 and ketogenic diets in Alzheimer's disease
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Award Amount
$708,558.00
Ceiling
$708,558.00
Awarded
April 24, 2026
Identifier
11322757
Research project awarded to study the interaction of APOE4 genetic risk and ketogenic diets in Alzheimer's disease, aiming to find therapeutic and diagnostic advances.
Description
The project focuses on Alzheimer's disease, APOE4 genetic risk factor, diet interactions, cholesterol homeostasis, and neurodegeneration. The study involves in vitro human brain tissue models, humanized mice, and genetic risk factors. The project is funded by the National Institute on Aging (NIA), NIH. The project aims to identify therapeutic targets and diagnostic strategies related to diet and genetics in AD.