Award
National Institute of General Medical Sciences 5R35GM155165-03
Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis.
Recipient
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Award Amount
$389,997.00
Ceiling
$389,997.00
Awarded
May 01, 2026
Identifier
5R35GM155165-03
This award funds research to understand organ-specific microvascular endothelial responses in sepsis using translational approaches including single-cell transcriptomics, organoid disease models, and gene-editing techniques to develop targeted therapies.
Description
Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis. The project aims to address key knowledge gaps in sepsis treatment through discovery, disease models, and disease mechanisms to enhance understanding of organ-specific microvascular responses and inform development of precision therapies.