Award
National Institute of Allergy and Infectious Diseases 5R21AI184169-02
Impact of in utero HIV and antiretroviral exposure on the placenta and birth weight
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$191,450.00
Ceiling
$191,450.00
Awarded
January 22, 2026
Identifier
5R21AI184169-02
NIH-funded research project investigating the effects of in utero HIV and antiretroviral exposure on placental health and birth weight to optimize ARV use during pregnancy.
Description
This study will use stored blood and hair samples and clinical data from an ongoing birth cohort study to elucidate the independent effects of HIV and ARV exposure on the placenta and birth weight. The study aims to improve child health outcomes and inform ARV use during pregnancy by measuring ARV levels in dried blood spots and hair, analyzing placental histopathology, and relating these to birth outcomes in a cohort from Uganda.