Award
National Institute of Allergy and Infectious Diseases 5P01AI100148-13
Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1 Antibodies
Recipient
California Institute of Technology
Award Amount
$4,147,848.00
Ceiling
$4,147,848.00
Awarded
January 28, 2026
Identifier
5P01AI100148-13
NIH awarded a research project to California Institute of Technology to develop immunogens that elicit broadly neutralizing anti-HIV-1 antibodies, aiming to improve HIV vaccine efficacy through innovative vaccine designs and animal testing.
Description
A research project focused on HIV vaccine development involving designing immunogens and testing in animal models to elicit broadly neutralizing antibodies against HIV-1. The project builds on previous discoveries to design more strategic and effective priming and boosting immunogens using novel nanoparticle and mRNA-LNP vaccine designs.