Award
National Institute of Allergy and Infectious Diseases 5R37AI044170-27
Salmonella Host interactions
Recipient
National Institute of Allergy and Infectious Diseases (NIAID)
Award Amount
$619,850.00
Ceiling
$619,850.00
Awarded
January 09, 2026
Identifier
5R37AI044170-27
Award for developing a novel mouse model to study Salmonella Typhi infection mechanisms, focusing on virulence factors and pathogenesis.
Description
This project aims to develop a mouse model for oral S. Typhi infection to study virulence factors and pathogenesis. The project is innovative as it establishes the first mouse model for this purpose. The work involves studying the role of the Vi capsular polysaccharide and T3SS-2 in S. Typhi infection.