Award
NIH Reporter #5K99CA299410-02
Beyond Lysis: Deciphering the Role of Perforin-Mediated Ferroptosis in Anti-Tumor Immunity
Recipient
University of Michigan at Ann Arbor, Department of Surgery
Award Amount
$139,968.00
Ceiling
$139,968.00
Awarded
June 08, 2026
Identifier
5K99CA299410-02
NIH grant awarded to study how perforin induces ferroptosis in tumor cells to enhance anti-tumor immunity and develop new therapies.
Description
This NIH grant project aims to determine the mechanism and metabolic regulators of perforin-induced ferroptosis in tumor cells, with the goal of developing translational therapies to enhance perforin-induced ferroptosis and improve anti-tumor immunity.