Award
National Cancer Institute 5F30CA278322-03
Anti-Complement Immunotherapy for Pancreatic Cancer
Recipient
Albert Einstein College of Medicine
Award Amount
$55,114.00
Ceiling
$55,114.00
Awarded
January 07, 2026
Identifier
5F30CA278322-03
Research project funded by the National Cancer Institute to study complement activation in pancreatic cancer and develop immunotherapeutic strategies involving complement blockade and radiotherapy.
Description
The project aims to understand how complement activation in the tumor microenvironment promotes oncogenesis by signaling to immune cells and cancer-associated fibroblasts, and to explore translational therapeutics that blockade complement signaling, alone and in combination with radiotherapy, as potential immunotherapeutic strategies for pancreatic ductal adenocarcinoma (PDAC).