Award
National Institute of Allergy and Infectious Diseases 5R01AI177607-03
Mechanism For Merkel Cell Polyomavirus Persistence
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$738,023.00
Ceiling
$738,023.00
Awarded
December 05, 2025
Identifier
5R01AI177607-03
NIH awarded a research grant to University of Pittsburgh to study the mechanisms of MCPyV persistence and latency, aiming to understand viral replication control and its implications for cancer therapy.
Description
Research grant to investigate how Merkel cell polyomavirus (MCPyV) controls its replication to achieve persistence/latency using new technologies, including characterization of LT binding and helicase activity, CRISPR-Cas9 screening, and live cell imaging.