Award
National Heart, Lung, and Blood Institute 5R61HL175687-02
Cobinamide as a disease-modifying treatment for Marfan Syndrome: optimization of absorption
Recipient
University of California, San Diego, La Jolla, CA
Award Amount
$393,883.00
Ceiling
$393,883.00
Awarded
May 14, 2026
Identifier
5R61HL175687-02
This award supports research to enhance the intestinal absorption and bioavailability of cobinamide, a potential treatment for Marfan Syndrome, aiming to improve its effectiveness as a disease-modifying therapy.
Description
Research grant focused on improving bioavailability of cobinamide for potential therapeutic use in Marfan Syndrome by testing various ligands and permeation enhancers to optimize absorption and bioavailability.