Award
National Institute of Dental and Craniofacial Research 5R21DE033128-02
Repurposing Ferumoxytol Nanoparticles to Promote Orofacial Stem Cell Function for Autotherapies
Recipient
UNIVERSITY OF PENNSYLVANIA
Award Amount
$203,125.00
Ceiling
$203,125.00
Awarded
June 09, 2025
Identifier
5R21DE033128-02
Research project awarded to explore ferumoxytol nanoparticles for enhancing orofacial stem cell function and tissue regeneration.
Description
This project involves exploring the role of ferumoxytol in activating orofacial mesenchymal stem cells (MSCs) and promoting tissue regeneration through YAP/TAZ signaling pathways. The research includes in vitro characterization and in vivo mouse models to assess endogenous tissue regeneration capabilities.