Award
NIH Reporter #5R35GM151964-03
DelPhi and associated resources: maintenance, development and applications
Recipient
Clemson University, SC, United States
Award Amount
$378,378.00
Ceiling
$378,378.00
Awarded
January 27, 2026
Identifier
5R35GM151964-03
Award for the maintenance, development, and application of DelPhi software, focusing on electrostatics modeling and mutation effect prediction using advanced computational methods.
Description
This project involves the maintenance, development, and application of the DelPhi software package and related resources. The focus is on further developing Gaussian-based approaches for modeling biological macromolecules as inhomogeneous objects, and on predicting the effects of missense mutations on folding and binding free energies using combined first-principle and machine learning approaches.