Award
NIH Reporter #5R01CA297829-02
Growth suppressive and oncogenic transcriptional programs controlled by the androgen receptor in prostate cancer
Recipient
Weill Medical College of Cornell University
Award Amount
$564,543.00
Ceiling
$564,543.00
Awarded
February 27, 2026
Identifier
5R01CA297829-02
This NIH-funded project studies how the androgen receptor switches from suppressing growth to promoting cancer in prostate cells, aiming to find new therapies by reactivating normal AR functions.
Description
The project aims to define the factors mediating the switch of androgen receptor (AR) from growth suppressive to oncogenic in prostate cancer, exploring reactivation of normal AR programs to halt progression. It involves studying AR reprogramming, epigenomic modulation, and therapeutic targeting.