Award
National Heart, Lung, and Blood Institute 1R01HL186673-01
Termination of lung inflammation by MyD88 alternative splicing
Recipient
NATIONAL JEWISH HEALTH, DENVER, CO, UNITED STATES
Award Amount
$1,559,468.00
Ceiling
$1,559,468.00
Awarded
July 16, 2026
Identifier
1R01HL186673-01
This award funds research on the role of MyD88 alternative splicing in lung inflammation, including creating a mouse model to study its function, with a project duration from July 2026 to June 2028.
Description
The project investigates the physiological effect of altered RNA processing of MyD88, focusing on its role in modulating inflammatory responses in lung diseases. The project aims to understand the role of MyD88 alternative splicing in lung inflammation. The project involves generating a mouse model lacking MyD88-S to test hypotheses about its function. The project is funded for a multiyear period starting July 2026 and is managed by the NHLBI in collaboration with the National Jewish Health organization.