Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK137983-02
CYP4F Enzymes Regulate N-Acyl Amino Acid Signaling in Humans
Recipient
Beth Israel Deaconess Medical Center
Award Amount
$731,254.00
Ceiling
$731,254.00
Awarded
December 15, 2025
Identifier
5R01DK137983-02
NIH research grant to study the regulation of N-acyl amino acids by CYP4F enzymes in humans, focusing on biochemical characterization, cellular metabolism, and biomarker identification related to obesity and type 2 diabetes.
Description
This project investigates how N-acyl amino acids, signaling molecules in the blood with anti-diabetic properties, are regulated by CYP4F enzymes in humans. The research aims to characterize these interactions biochemically, understand their effects on cellular metabolism, and identify biomarkers of cardiometabolic disease.