Award
National Institute on Drug Abuse 5K01DA053434-05
Cell-Types Specific Neuroadaptations in the Nucleus Accumbens Shell Associated with Individual Differences in Cocaine-Seeking
Recipient
National Institute on Drug Abuse (NIDA)
Award Amount
$196,934.00
Ceiling
$196,934.00
Awarded
April 08, 2025
Identifier
5K01DA053434-05
Research project funded by the National Institute on Drug Abuse to study neuroadaptations in the nucleus accumbens shell related to cocaine-seeking behavior using advanced neurobiological methods.
Description
The project focuses on cellular substrates associated with cocaine aversion and neural adaptations in the nucleus accumbens shell. The research involves fiber photometric and optogenetic methods. The project aims to understand the cellular and molecular mechanisms underlying individual differences in cocaine-seeking behavior. It includes aims to analyze cell-specific gene translation and manipulate RhoA activity in specific neuron types.