Award
NIH Reporter #1F31AI186450-01A1
Analyzing Spatial Movement Patterns and Transmission Hotspots to Inform Targeted Case-Finding Interventions in KwaZulu-Natal, South Africa
Recipient
Columbia University Health Sciences
Award Amount
$49,538.00
Ceiling
$49,538.00
Awarded
August 26, 2025
Identifier
1F31AI186450-01A1
A research project funded by NIAID to study spatial mobility patterns and TB transmission hotspots in KwaZulu-Natal, South Africa, using mobility data and genomic sequencing to inform targeted interventions.
Description
This project aims to combine spatial mobility data with bacterial whole genome sequencing to understand TB transmission dynamics and identify hotspots for targeted interventions in KwaZulu-Natal, South Africa. The study will characterize forms of spatial mobility and their association with recent transmission, and examine the relationship between spatial mobility subclasses and community-based TB transmission hotspots. The research leverages detailed mobility data and genomic statistical modeling to inform targeted case-finding strategies to curb ongoing TB transmission.