Award
National Heart, Lung, and Blood Institute 5K01HL171464-02
Optimization and development of extracellular matrix-targeting probes for PET-based assessment of lung fibrosis disease activity
Recipient
University of Wisconsin-Madison
Award Amount
$130,350.00
Ceiling
$130,350.00
Awarded
August 20, 2025
Identifier
5K01HL171464-02
The award supports the development of a novel PET probe to non-invasively assess lung fibrosis disease activity, enabling better diagnosis and treatment monitoring of IPF.
Description
This project aims to develop a PET imaging probe targeting fibronectin to assess lung fibrosis activity, with potential for clinical translation to improve diagnosis and treatment monitoring of idiopathic pulmonary fibrosis (IPF). The project will optimize the probe's imaging performance and determine its ability to monitor disease progression and response to antifibrotic therapies.