Award

NIH Reporter #1R01HG014500-01

3D Chromatin architectural dynamics at ultra-high resolution

Recipient

Not specified

Award Amount

$863,248.00

Ceiling

$863,248.00

Awarded

January 30, 2026

Identifier

1R01HG014500-01

NIH grant awarded for research on 3D chromatin architecture using advanced techniques including ultra-high resolution RCMC and machine learning, focusing on genome folding and chromatin dynamics.

Description

This is a NIH grant project for research on 3D genome folding and chromatin dynamics, with a focus on microcompartments, heterochromatin, and super-resolution chromosome tracing. The project involves advanced techniques such as ultra-high resolution Region Capture Micro-C (RCMC), machine learning-based imputation, and mechanistic 3D polymer modeling.

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