Award
National Institute of Dental and Craniofacial Research 1R56DE033716-01A1
Irx1 regulation of oral tissue repair and maintenance.
Recipient
University of Iowa
Award Amount
$480,840.00
Ceiling
$480,840.00
Awarded
May 07, 2025
Identifier
1R56DE033716-01A1
The award supports research on the role of Irx1 in oral tissue repair and maintenance, focusing on its regulation of oral wound healing and stem cell niche activity in the oral epithelium.
Description
This project aims to determine if oral wound healing is regulated by Irx1, a progenitor cell transcription factor. Irx1 may mark oral stem cell niches and regulate cell proliferation and differentiation in the oral epithelium. The study will investigate Irx1's role in controlling repair and regeneration of the oral epithelium.