Award
NIH Reporter #R01DK146350-01A1
Alternative splicing of UMOD as a protective mechanism for thick ascending cells in kidney injury.
Recipient
Indiana University Indianapolis
Award Amount
$674,691.00
Ceiling
$674,691.00
Awarded
August 19, 2026
Identifier
R01DK146350-01A1
NIH grant awarded to Indiana University Indianapolis for research on Uromodulin's role in kidney injury, with a focus on alternative splicing as a protective mechanism. The project runs from August 2026 to March 2030 with an award amount of approximately $674,691 for FY 2026.
Description
This NIH grant supports research on the role of a protein, Uromodulin, in kidney injury, focusing on a splice variant AS-UMOD. The project involves innovative tools such as splice switching oligonucleotides, fluorescence imaging, and spatial metabolomics.