Award
National Human Genome Research Institute 3U01HG011967-05S1
Design, prediction, and prioritization of systematic perturbations of the human genome
Recipient
Duke University
Award Amount
$665,995.00
Ceiling
$665,995.00
Awarded
June 05, 2026
Identifier
3U01HG011967-05S1
This NIH-funded project at Duke University develops machine learning and statistical methods to annotate and predict the functional impact of noncoding genetic variants, improving understanding of genetic causes of disease and aiding diagnosis and treatment.
Description
The project aims to develop a systematic and comprehensive approach for interpreting noncoding variants to understand the mechanisms linking genetics to gene expression and human disease. The outcomes will transform disease studies by enabling noncoding sequence variation to inform genetic causes of disease, aiding in gene discovery and diagnostic interpretation.