Award
National Heart, Lung, and Blood Institute 5U24HL141732-06
2/2 PROmote weight loss in obese PAD patients to preVEnt mobility loss: The PROVE Trial--DCC
Recipient
Not Specified
Award Amount
$200,993.00
Ceiling
$200,993.00
Awarded
June 30, 2025
Identifier
5U24HL141732-06
Award for the Data Coordinating Center of a clinical trial studying weight loss and exercise interventions in obese patients with peripheral artery disease, focusing on mobility outcomes over 12 months.
Description
The project involves serving as the Data Coordinating Center (DCC) for a clinical trial comparing weight loss plus exercise intervention with exercise only in obese patients with peripheral artery disease. The primary outcome is 12-month change in the 6-minute walk. The project includes developing a web-based data management system, overseeing quality control, analyzing data, and manuscript preparation. The project team has experience with multi-center trials, cardiovascular disease, exercise, and weight loss trials, emphasizing innovation in web-based trial management and electronic data capture.