Award
NIH Reporter #1R21NS144989-01A1
Evaluation and discovery of blood-based biomarkers for ataxia
Recipient
University of California Los Angeles, Department of Neurology
Award Amount
$196,875.00
Ceiling
$196,875.00
Awarded
May 18, 2026
Identifier
1R21NS144989-01A1
A research grant awarded to discover and validate blood-based biomarkers for ataxia to aid in diagnosis and therapy development.
Description
This project aims to discover and validate blood-based biomarkers for ataxia severity and progression using proteomic and transcriptomic approaches, including proximity extension proteomics, RNA sequencing, and immunoassays. The study will analyze patient plasma and neuronal extracellular vesicles to identify biochemical changes in the central nervous system, facilitating future clinical trials and therapy development.