Award
National Institute on Drug Abuse 1R01DA063428-01A1
Neural circuit mechanisms of inflexible drug seeking in a model of HIV infection
Recipient
Drexel University
Award Amount
$445,636.00
Ceiling
$445,636.00
Awarded
May 13, 2026
Identifier
1R01DA063428-01A1
This NIH-funded project aims to study neural circuit mechanisms underlying inflexible drug seeking behavior in a mouse model of HIV infection, focusing on cocaine use disorder and related neurocircuit dysregulation.
Description
The project investigates neurocircuit dysregulation during cocaine self-administration and related behaviors in a mouse model of HIV infection using in vivo electrophysiology, tract tracing, pharmacology, and chemogenetics to understand drug seeking behavior in the context of HIV infection.