Award
NIH Reporter #5K99DK140516-02
Mechanisms of Cellular Communication: The Role of Merlin in Pancreatic Development
Recipient
UT Southwestern Medical Center
Award Amount
$89,424.00
Ceiling
$89,424.00
Awarded
August 14, 2026
Identifier
5K99DK140516-02
Research investigating how Merlin interprets biomechanical signals to regulate pancreatic development and progenitor cell differentiation, with potential relevance to diabetes regenerative therapies.
Description
The project examines Merlin's role in pancreatic development, including how mechanical cues and Hippo signaling affect pancreatic morphogenesis, lumen formation, and cell differentiation.