Award
National Institute on Aging 1R21AG084916-01A1
'Omics predictors of Sickle Cell Severity and Survival
Recipient
Duke University, Durham, NC
Award Amount
$430,956.00
Ceiling
$430,956.00
Awarded
July 17, 2024
Identifier
1R21AG084916-01A1
NIH awarded a grant to Duke University to study multi-omic predictors of severity and survival in sickle cell disease, aiming to identify biomarkers for early mortality and improve personalized care.
Description
This NIH grant project aims to identify multi-omic risk factors and biomarkers for organ dysfunction and early mortality in sickle cell disease (SCD), facilitating personalized medicine approaches. The study leverages data from over 4000 samples including whole genome sequencing and clinical data to understand survival variability and aging pace in SCD patients.