Award
National Heart, Lung, and Blood Institute PA-23-272
Mechanosensitive Mechanisms of Premature Calcification in Bicuspid Aortic Valve Disease
Recipient
Medical College of Wisconsin
Awarded
May 19, 2026
Identifier
PA-23-272
NIH project investigating biomechanical and molecular mechanisms of premature calcification in bicuspid aortic valve disease to identify therapeutic targets.
Description
This NIH-funded project, led by Makenna Christine Blair at the Medical College of Wisconsin, aims to elucidate the signaling pathways involved in early calcification of the aortic valve in patients with bicuspid aortic valve disease. The study combines computational and experimental approaches to identify potential therapeutic targets.