Award
National Institute of Diabetes and Digestive and Kidney Diseases 5K08DK134879-04
Rac1 and the actin cytoskeleton in renal tubular repair
Recipient
Vanderbilt University Medical Center
Award Amount
$158,544.00
Ceiling
$158,544.00
Awarded
May 28, 2026
Identifier
5K08DK134879-04
The award supports research on how Rac1 regulates the actin cytoskeleton and cell cycle during kidney epithelial repair, aiming to understand molecular mechanisms critical for kidney regeneration after injury.
Description
This project investigates the role of Rac1, a small Rho GTPase, in regulating the actin cytoskeleton during renal epithelial repair. The study aims to define the mechanisms by which Rac1 controls renal epithelial repair and mitotic morphology, which are critical for kidney tissue regeneration and function.