Award

National Institute of Neurological Disorders and Stroke 5R01NS136743-02

Improving the sensitivity and specificity of diffusion MRI

Recipient

Vanderbilt University, Nashville, TN

Award Amount

$596,096.00

Ceiling

$596,096.00

Awarded

April 01, 2026

Identifier

5R01NS136743-02

NIH grant awarded to Vanderbilt University to develop and validate advanced diffusion MRI methods for better brain imaging and injury detection.

Description

This project aims to improve the detection of fiber pathways and tissue microstructure in vivo using diffusion MRI (DMRI). It seeks to develop and validate advanced methods for fiber identification and tissue characterization, assess the reproducibility of fiber-specific diffusion properties, and quantify intersubject variability. The research will enhance DMRI's sensitivity to white matter injury and improve the specificity of imaging biomarkers for brain injury, recovery, and aging.

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