Award
National Cancer Institute 5R01CA231321-06
Role of Circadian Factors in Inflammation and Colorectal Adenoma Risk
Recipient
Virginia Commonwealth University
Award Amount
$243,641.00
Ceiling
$243,641.00
Awarded
August 19, 2024
Identifier
5R01CA231321-06
NIH awarded $243,641 to Virginia Commonwealth University for a study on circadian factors affecting inflammation and colorectal adenoma risk, focusing on racial disparities and molecular mechanisms.
Description
This NIH-funded research project focuses on molecular and behavioral factors influencing colorectal cancer risk, with an emphasis on racial disparities and circadian biology. The study employs a biobehavioral case-control design to investigate whether disruptions in circadian rhythms and sleep, including genetic and epigenetic factors, are associated with inflammation and colorectal adenomas among African- and European-American patients undergoing screening colonoscopy. The research aims to identify modifiable risk factors and potential targets for colorectal cancer prevention.