Award
National Institute of Diabetes and Digestive and Kidney Diseases RFA-NS-22-034
PNPase inhibition as an effective treatment for chronic bladder pain
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$1,571,034.00
Ceiling
$1,571,034.00
Awarded
August 07, 2025
Identifier
RFA-NS-22-034
Award for research on PNPase inhibition as a treatment for chronic bladder pain, focusing on IC/BPS using rodent models and patient samples, funded by NIDDK.
Description
The project focuses on validating purine nucleoside phosphorylase (PNPase) as a therapeutic target for visceral pain disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS). The research involves rodent models and exosome analysis from patient samples. The project aims to shift current paradigms in research and clinical practice for IC/BPS.