Award
NIH Reporter #5R21DA059363-03
Nucleophile-Fragment Screening for Site-Specific Covalent Ligand Discovery in Opioid Receptor Signaling
Recipient
Florida Atlantic University, Boca Raton, FL, United States
Award Amount
$190,625.00
Ceiling
$190,625.00
Awarded
March 19, 2025
Identifier
5R21DA059363-03
Research project funded by the National Institute on Drug Abuse to develop chemoproteomics approaches for discovering covalent ligands targeting opioid receptor signaling, aiming to identify potential therapeutics for opioid dependence.
Description
This project involves chemoproteomics, covalent ligand discovery, and opioid receptor signaling research, funded by NIH/NIDA, with a focus on redox-active cysteines in neuronal models.