Award
National Cancer Institute 5U01CA261339-05
Leveraging Prospective Cancer Epidemiology Cohorts and Novel Methods to Improve Polygenic Risk Scores
Recipient
National Cancer Institute (NCI), part of the National Institutes of Health (NIH)
Awarded
August 18, 2025
Identifier
5U01CA261339-05
NIH National Cancer Institute project to develop and evaluate polygenic risk scores across diverse racial/ethnic groups using large-scale cohorts to improve cancer risk prediction and address health disparities.
Description
This NIH-funded project by the National Cancer Institute involves developing methods to construct and evaluate polygenic risk scores in multiethnic populations, utilizing cohorts such as MEC, GERA, WHI, NHS, HPFS, and PLCO, including over 300,000 individuals. The project emphasizes inclusivity of diverse populations to enhance the translational potential of genomic medicine in cancer risk assessment.