Award
NIH Reporter #2R01MH125772-22A1
Presynaptic forms of long-term plasticity in the CNS
Recipient
Albert Einstein College of Medicine, Bronx, NY, United States
Award Amount
$741,766.00
Ceiling
$741,766.00
Awarded
September 02, 2026
Identifier
2R01MH125772-22A1
This award funds research to understand the role of presynaptic local protein synthesis in synaptic plasticity and its implications for brain disorders, aiming to uncover mechanisms that could lead to novel therapeutic targets.
Description
The proposed studies aim to investigate how synaptic protein synthesis contributes to brain adaptations in health and disease, focusing on presynaptic local protein synthesis in the mature mammalian brain and its role in synaptic plasticity, behavior, and brain disorders such as intellectual disabilities, autism spectrum disorder, depression, and epilepsy.