Award

National Heart, Lung, and Blood Institute 5R01HL169631-03

Managing Alpha-1-Antitrypsin Deficiency (AATD) through Proteostasis Signaling Pathways

Recipient

William Edward Balch

Award Amount

$855,694.00

Ceiling

$855,694.00

Awarded

February 27, 2026

Identifier

5R01HL169631-03

NIH grant awarded by NHLBI for research on therapeutic approaches to Alpha-1-antitrypsin deficiency using proteostasis signaling pathways, with an award amount of $855,694.

Description

This is a NIH grant project focused on developing therapeutic approaches for Alpha-1-antitrypsin deficiency through manipulation of proteostasis signaling pathways, involving small molecule activators and Gaussian process machine learning tools. The project is funded by NHLBI with a total award amount of $855,694 for fiscal year 2026.

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