Award
National Institute of Allergy and Infectious Diseases 5R01AI163517-05
Effect of Th2-type microenvironment on CD8 TRM-mediated protection from infection
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$579,303.00
Ceiling
$579,303.00
Awarded
April 24, 2026
Identifier
5R01AI163517-05
This NIH-funded research project investigates how a Th2-type microenvironment affects CD8 tissue resident memory T cells and their role in protecting against infections, particularly in patients with atopic dermatitis.
Description
Research project to determine whether the local tissue environment impairs the persistence or function of immune cells within the skin of patients with allergic diseases, aiming to develop novel therapies to improve protection from infection in these patients.