Award
National Institute of General Medical Sciences 5R35GM150625-03
Using Experimental Evolution to Evaluate Environmental Effects on Microbial Mutation and Adaptation
Recipient
Vanderbilt University
Award Amount
$396,127.00
Ceiling
$396,127.00
Awarded
July 23, 2025
Identifier
5R35GM150625-03
NIH grant awarded to Vanderbilt University to study microbial adaptation and evolution under varying oxygen conditions using experimental evolution techniques.
Description
This NIH grant project investigates how microbes adapt and diversify in complex environments, focusing on the effects of oxygen availability on microbial evolution to feast/famine conditions using experimental evolution with Escherichia coli and Lactobacillus crispatus. The study aims to provide fundamental knowledge about evolutionary processes in microbial environments relevant to the human microbiome.