Award
NIH Reporter #11376435
Delineating systemic roles of APOE genotypes on CNS health
Recipient
Not specified
Award Amount
$2,944,007.00
Ceiling
$2,944,007.00
Awarded
June 03, 2026
Identifier
11376435
This award funds research to study the systemic effects of APOE genotypes on central nervous system health, particularly their influence on brain function and Alzheimer's disease pathology.
Description
The project focuses on the systemic roles of APOE genotypes on CNS health, with specific aims to analyze blood-borne mediators related to APOE4 and APOE3, and their impact on brain function and AD pathology. The project involves advanced transcriptomic, behavioral, and morphometric approaches.