Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 1R03HD113887-01A1
ZFHX4 sets alveolar fibroblast differentiation potential of mesenchymal progenitors in the fetal lung
Recipient
Massachusetts General Hospital
Award Amount
$164,990.00
Ceiling
$164,990.00
Awarded
July 30, 2024
Identifier
1R03HD113887-01A1
NIH awarded a grant to Massachusetts General Hospital to study the role of the gene ZFHX4 in fetal lung development, particularly its impact on alveolar fibroblast differentiation and lung hypoplasia in CDH.
Description
This NIH R03 grant supports research on the role of ZFHX4 in lung development, focusing on alveolar fibroblast differentiation using molecular and genetic approaches in mouse models. The project investigates the role of the CDH-associated gene ZFHX4 in fetal lung development to understand lung hypoplasia in congenital diaphragmatic hernia (CDH).