Award
NIH Reporter #5R01AI186276-02
Exogenous fatty acid utilization by Staphylococcus aureus
Recipient
University of Kansas Medical Center, Kansas City, KS, United States
Award Amount
$597,710.00
Ceiling
$597,710.00
Awarded
July 27, 2026
Identifier
5R01AI186276-02
Research project funded by NIAID to study fatty acid utilization mechanisms in Staphylococcus aureus, including the FakAB system, fatty acid degradation, and gene expression responses, to better understand bacterial physiology and potential therapeutic targets.
Description
This project investigates how Staphylococcus aureus utilizes exogenous fatty acids, focusing on the FakAB system for incorporation of fatty acids into lipids, a potential fatty acid degradation pathway, and the transcriptional response of S. aureus to fatty acids. The research aims to clarify mechanisms of fatty acid utilization and gene expression impact in this pathogen.